An acylindrical action generalizes proper and cobounded actions on hyperbolic spaces. Non-elementary acylindrical actions provide acylindrically hyperbolic groups, which includes most mapping class groups of punctured surfaces, 3-manifold groups, and $Out(F_n)$ for $n>1$. In this talk, we will explore how acylindricity of a group action on a tree can be preserved under quotients by certain subgroups, and discuss the existence of a largest acylindrical action for some groups acting on trees. In addition, we will show when $Out(BS(p,q))$ is acylindrically hyperbolic for non-solvable Baumslag-Solitar groups, despite $BS(p,q)$ itself not being acylindrically hyperbolic, and explore further applications of these acylindricity results. This is a joint work with Daxun Wang.